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Kanglongpharma was founded in 2001 and through 18years of experience,we are now a leading manufacturer of pharmaceutical packing area.We specialize in butyl rubber stopper for blood collection tube,butyl rubber stopper for infusion...

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What are the chemical compatibility considerations when choosing a coated rubber stopper

When choosing a coated rubber stopper, it is important to consider the chemical compatibility of the stopper with the sample or solution it will come into contact with. This is because certain chemicals can react with the rubber or coating, causing degradation or contamination of the sample. Here are some chemical compatibility considerations to keep in mind:
Compatibility of the rubber material: Rubber stoppers are typically made from materials such as silicone, natural rubber, or synthetic rubber. Each material has different chemical compatibility properties, so it's important to choose a material that is compatible with your sample. For example, natural rubber is not recommended for use with most organic solvents, while silicone is generally more chemically resistant.
Compatibility of the coating: Coated rubber stoppers may have a coating that provides additional chemical resistance or barrier properties. It is important to ensure that the coating material is compatible with the sample or solution it will come into contact with. Some common coatings include PTFE (polytetrafluoroethylene), which is highly resistant to most chemicals, and epoxy, which is durable and resistant to solvents.
Compatibility of the sample or solution: It is important to consider the chemical properties of the sample or solution, including its pH, temperature, and chemical composition. Some chemicals may react with the rubber or coating material, causing degradation or contamination of the sample. It is important to consult chemical compatibility charts and conduct compatibility testing to ensure that the rubber stopper is suitable for use with your sample.
To ensure compatibility with your sample or solution, you can consult chemical compatibility charts or contact the manufacturer of the rubber stopper. Additionally, it is important to conduct compatibility testing by placing the stopper in contact with the sample or solution for a period of time and observing any changes or reactions. By carefully considering chemical compatibility factors and conducting compatibility testing, you can ensure that your coated rubber stopper is compatible with your sample and will not cause contamination or degradation.
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